Managing Opioid-Induced Constipation in Ambulatory-Care Patients
نویسنده
چکیده
Introduction ..................................................... 1 Functional Constipation .................................. 2 Opioid-Induced Constipation........................... 2 Prevalence .................................................. 3 Role of Opioid Receptors............................ 3 Differential Opioid Effects ........................... 3 Patient Assessment & Treatment.................... 4 Prevention................................................... 4 Non-Pharmacologic Tx: Myths & Facts....... 4 Pharmacologic Tx: Laxatives ...................... 5 Alternative Pharmacotherapies....................... 7 Opioid-Receptor Antagonists ...................... 7 Selective Antagonists.................................. 7 Prokinetic Agents ........................................ 7 Summary......................................................... 7 References...................................................... 8
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